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Cost-Effectiveness in Health and Medicine - Oxford Scholarship Online
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Cost-Effectiveness in Health and Medicine

Peter J. Neumann, Theodore G. Ganiats, Louise B. Russell, Gillian D. Sanders, and Joanna E. Siegel


As healthcare costs rise in the United States, debate is ongoing over how to obtain better value for dollars spent. In this context, the use of cost-effectiveness analysis (CEA) is more compelling than ever. This book, written by the Second Panel on Cost-Effectiveness in Health and Medicine, reviews key concepts and analytic challenges in CEA. The authors endorse the original Panel’s concept of a reference case and support its recommendation that analysts take a broad societal perspective; in addition, they recommend a healthcare sector perspective for a second reference case, as well as an im ... More

Keywords: Cost-effectiveness analysis, reference case, healthcare perspective, societal perspective, Impact Inventory, recommendations

Bibliographic Information

Print publication date: 2016 Print ISBN-13: 9780190492939
Published to Oxford Scholarship Online: November 2016 DOI:10.1093/acprof:oso/9780190492939.001.0001


Affiliations are at time of print publication.

Peter J. Neumann, editor
Director of the Center for the Evaluation of Value and Risk in Health and Professor of Medicine, Tufts Medical Center and Tufts University

Theodore G. Ganiats, editor
Professor Emeritus, Health Services Research Center and Department of Family Medicine and Public Health, University of California, San Diego

Louise B. Russell, editor
Distinguished Professor, Institute for Health and Department of Economics, Rutgers University

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1 Using Cost-Effectiveness Analysis in Health and Medicine

Peter J. Neumann, Louise B. Russell, Joanna E. Siegel, Lisa A. Prosser, Murray Krahn, Jeanne S. Mandelblatt, Norman Daniels, and Marthe R. Gold

2 Theoretical Foundations of Cost-Effectiveness Analysis in Health and Medicine

David O. Meltzer, Anirban Basu, and Mark J. Sculpher

3 Recommendations on Perspectives for the Reference Case

Peter J. Neumann, Gillian D. Sanders, Anirban Basu, Dan W. Brock, David Feeny, Murray Krahn, Karen M. Kuntz, David O. Meltzer, Douglas K. Owens, Lisa A. Prosser, Joshua A. Salomon, Mark J. Sculpher, Thomas A. Trikalinos, Louise B. Russell, Joanna E. Siegel, and Theodore G. Ganiats

4 Designing a Cost-Effectiveness Analysis

Douglas K. Owens, Joanna E. Siegel, Mark J. Sculpher, and Joshua A. Salomon

5 Decision Models in Cost-Effectiveness Analysis

Karen M. Kuntz, Louise B. Russell, Douglas K. Owens, Gillian D. Sanders, Thomas A. Trikalinos, and Joshua A. Salomon

6 Identifying and Quantifying the Consequences of Interventions

Joshua A. Salomon, Thomas A. Trikalinos, Gillian D. Sanders, and Jeanne S. Mandelblatt

7 Valuing Health Outcomes

David Feeny, Murray Krahn, Lisa A. Prosser, and Joshua A. Salomon

9 Evidence Synthesis for Informing Cost-Effectiveness Analysis

Thomas A. Trikalinos, Louise B. Russell, and Gillian D. Sanders

10 Discounting in Cost-Effectiveness Analysis

Anirban Basu and Theodore G. Ganiats

11 Reflecting Uncertainty in Cost-Effectiveness Analysis

Mark J. Sculpher, Anirban Basu, Karen M. Kuntz, and David O. Meltzer

12 Ethical and Distributive Considerations

Dan W. Brock, Norman Daniels, Peter J. Neumann, and Joanna E. Siegel

13 Reporting Cost-Effectiveness Analyses

Lisa A. Prosser, Peter J. Neumann, Gillian D. Sanders, and Joanna E. Siegel