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Cost-Effectiveness in Health and Medicine$
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Peter J. Neumann, Theodore G. Ganiats, Louise B. Russell, Gillian D. Sanders, and Joanna E. Siegel

Print publication date: 2016

Print ISBN-13: 9780190492939

Published to Oxford Scholarship Online: November 2016

DOI: 10.1093/acprof:oso/9780190492939.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 31 October 2020

Designing a Cost-Effectiveness Analysis

Designing a Cost-Effectiveness Analysis

(p.75) 4 Designing a Cost-Effectiveness Analysis
Cost-Effectiveness in Health and Medicine

Douglas K. Owens

Joanna E. Siegel

Mark J. Sculpher

Joshua A. Salomon

Oxford University Press

This chapter provides an overview of how to design a cost-effectiveness analysis (CEA). The chapter highlights the importance of early conceptualization and planning steps to define the objectives, the research question, the perspective(s), the intervention(s), the target population, the comparators, the scope, the time horizon, and the analysis plan for a cost-effectiveness study. The chapter recommends that analysts conduct Reference Case analyses from both the healthcare sector perspective and the societal perspective. We also recommend that analysts use an Impact Inventory, which lists the consequences across sectors (e.g., healthcare, education, criminal justice system) affected by an intervention, and that they develop a written protocol that details key aspects of the CEA’s design and conduct.

Keywords:   Cost-effectiveness analysis, design, objectives, intervention, target population, comparators, time horizon, analysis plan, Reference Case, written protocol

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