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Migraine: A Spectrum of Ideas$
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Merton Sandler and Geralyn M. Collins

Print publication date: 1990

Print ISBN-13: 9780192618108

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780192618108.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 27 July 2021

A note on the role of platelets in migraine: a personal view

A note on the role of platelets in migraine: a personal view

(p.264) 22. A note on the role of platelets in migraine: a personal view
Migraine: A Spectrum of Ideas

Richard C. Peatfield

Oxford University Press

This chapter presents a personal view on the role of platelets in migraine. The chapter states a belief that much of the pathogenesis of each feature of migraine must relate to feedback loops. There must be two of these to account for the fact that the side affected by aura symptoms is not always the side affected by the headache. Each feedback loop must be able to enhance responses on one side at the expense of the other, and a loop eliminates the need to advance a single cause of migraine.

Keywords:   platelets, migraine, feedback loops, aura symptoms, pathogenesis, prophylactic drugs

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