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Design Concepts in Nutritional Epidemiology$
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Barrie M. Margetts and Michael Nelson

Print publication date: 1997

Print ISBN-13: 9780192627391

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780192627391.001.0001

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14. Cohort studies

14. Cohort studies

(p.383) 14. Cohort studies
Design Concepts in Nutritional Epidemiology

Michael L. Burr

Oxford University Press

Cohort studies follow a group of individuals over time to identify changes in status (such as disease or mortality) and relate these to observations made at baseline. They can also be carried out where observations on a group of individuals have been collected in the past and can be related to their current status. This chapter summarizes the strengths and weaknesses of cohort studies, and looks in detail at some of the practical issues in their implementation. Their implementation is illustrated using studies in both infancy and childhood and in middle-aged adults and the elderly. The issue of confounding is discussed. Details of study design are summarized in a checklist for planning a cohort study, and their statistical analysis considered in detail.

Keywords:   cohort study, hypothesis testing, cases, controls, confounding, statistical techniques

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