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Where's the Evidence?Debates in Modern Medicine$
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William A. Silverman

Print publication date: 1999

Print ISBN-13: 9780192630889

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780192630889.001.0001

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Begin with ‘If…’

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Where's the Evidence?

William A. Silverman

Oxford University Press

This chapter presents a 1989 commentary on randomized clinical trials. It argues that given the uncertainties about the wide extrapolation of results after any and all formal clinical studies, it makes sense to consider a graded approach to the release of a promising approach for everyday use. Instead of country-wide release, in a step-wise plan new treatment would be made available in only one city or other specific region in order to closely monitor the initial field experience with unselected patients.

Keywords:   medical practice, medical research, randomized clinical trials, graded approach, country-wide release

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