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Receptor and Ion-Channel Trafficking – Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels - Oxford Scholarship Online
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Receptor and Ion-Channel Trafficking: Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels

Stephen J. Moss and Jeremy Henley


This book reviews the recent advances in understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting, and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improved understanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states. The first section of the book contains three chapters dealing with cation channels and provides an account of what is known about the structures and the assembly and targeting of these mul ... More

Keywords: protein complexes, ion channels, receptor families, synaptic function, disease states, cation channels, multimeric proteins, acetylcholine receptors, amino acid receptors, molecular neurobiology

Bibliographic Information

Print publication date: 2002 Print ISBN-13: 9780192632241
Published to Oxford Scholarship Online: March 2012 DOI:10.1093/acprof:oso/9780192632241.001.0001


Affiliations are at time of print publication.

Stephen J. Moss, editor
MRC-LMCB & Department of Pharmacology, University College London, UK

Jeremy Henley, editor
MRC Centre for Synaptic Plasticity, School of Medical Sciences, University of Bristol, UK

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