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Receptor and Ion-Channel TraffickingCell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels$
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Stephen J. Moss and Jeremy Henley

Print publication date: 2002

Print ISBN-13: 9780192632241

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780192632241.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 24 October 2020

Ampa/kainate receptors

Ampa/kainate receptors

(p.130) (p.131) Chapter 6 Ampa/kainate receptors
Receptor and Ion-Channel Trafficking

Nicole L. Stricker

Richard L. Huganir

Oxford University Press

The three major types of ionotropic glutamate receptors are the N-methyl-d-aspartate (NMDAR), α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPAR), and kainate (KAR) receptors. AM PARs and KARs mediate fast excitatory transmission, whereas NMDARs mediate a slower component of synaptic transmission which is important for modulation of synaptic and neuronal function. This chapter focuses on the mechanisms of AMPA and kainate glutamate receptor assembly, synaptic localization, and surface expression.

Keywords:   ionotropic glutamate receptors, NMDAR, AMPAR, kainate glutamate receptors, synaptic localization, surface expression, neuronal function

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