Jump to ContentJump to Main Navigation
BioelectromagnetismPrinciples and Applications of Bioelectric and Biomagnetic Fields$
Users without a subscription are not able to see the full content.

Jaakko Malmivuo and Robert Plonsey

Print publication date: 1995

Print ISBN-13: 9780195058239

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780195058239.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 25 February 2021

Active Behavior of the Membrane

Active Behavior of the Membrane

Chapter:
(p.66) Chapter 4 Active Behavior of the Membrane
Source:
Bioelectromagnetism
Author(s):

Jaakko Malmivuo

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195058239.003.0004

This chapter describes the voltage clamp device, the experiments of Hodgkin and Huxley, the mathematical model into which their data were fitted, and the resulting simulation of a wide variety of recognized electrophysiological phenomena (activation, propagation, etc.). The voltage clamp procedure was developed in 1949. Because of its importance, this chapter first discusses the principle of the voltage clamp method in detail. The Hodgkin and Huxley work is important not only for its ability to describe quantitatively both the active and the passive membrane, but for its contribution to a deeper understanding of the membrane mechanisms that underlie its electrophysiological behavior.

Keywords:   electrophysiology, Hodgkin and Huxley experiments, voltage clamp, active membrane, passive membrane, stimulation

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .