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The AxonStructure, Function and Pathophysiology$
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Stephen G. Waxman, Jeffery D. Kocsis, and Peter K. Stys

Print publication date: 1995

Print ISBN-13: 9780195082937

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195082937.001.0001

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Development of axons: Calcium, steering, and the growth cone

Development of axons: Calcium, steering, and the growth cone

(p.200) 10 Development of axons: Calcium, steering, and the growth cone
The Axon




Oxford University Press

This chapter examines the control mechanisms underlying the establishment, modification, and repair of nervous systems as they reside at the level of the neuronal growth cone. It begins with a brief history and then outlines some of the essential morphological and structural features of neuronal growth cones. It discusses recent studies of the effects that physiological guidance cues exert on growth cone behavior and the role of the intracellular messenger calcium in controlling both overall growth cone behavior and neuronal pathfinding.

Keywords:   nervous systems, neuronal growth cone, intracellular messenger calcium, morphological features, structural features

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