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The AxonStructure, Function and Pathophysiology$
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Stephen G. Waxman, Jeffery D. Kocsis, and Peter K. Stys

Print publication date: 1995

Print ISBN-13: 9780195082937

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195082937.001.0001

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Ion pumps and exchangers

Ion pumps and exchangers

Chapter:
(p.296) 15 Ion pumps and exchangers
Source:
The Axon
Author(s):

PETER K. STYS

STEPHEN G. WAXMAN

BRUCE R. RANSOM

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195082937.003.0015

Excitable cells are dependent on adequate transmembrane ion gradients for normal function. Electrochemical gradients of the major cations (Na+, K+, Ca2+, and Mg2+) and anions (Cl- and HCO3 -) permit excitable cells to carry out signaling, sensory transduction, and effector functions. Axons are similarly dependent on the same ion gradients for their function. This chapter discusses transporting systems that function to maintain or restore gradients.

Keywords:   ion transport, electrochemical gradients, cations, anions, sensory transduction, effector functions

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