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Issues in Palliative Care Research$
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Russell K. Portenoy and Eduardo Bruera

Print publication date: 2003

Print ISBN-13: 9780195130652

Published to Oxford Scholarship Online: November 2011

DOI: 10.1093/acprof:oso/9780195130652.001.0001

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Fatigue in Medical Illness: Research Issues

Fatigue in Medical Illness: Research Issues

(p.151) 10 Fatigue in Medical Illness: Research Issues
Issues in Palliative Care Research

Russell K. Portenoy

Eduardo Bruera

Oxford University Press

Fatigue is a highly prevalent and complex symptom in populations with chronic illness. Although there have been significant advances in the methodologies to measure fatigue, few scientific investigations have focused on the nature of the problem and its management in clinical settings. In many ways, fatigue research is now at a point similar to pain research a quarter-century ago. Valid and reliable measurement is possible, and a growing number of epidemiological studies have established the seriousness of the clinical problem. The field is primed for studies that may illuminate the pathophysiology of the disorder in varied patient populations and provide an evidence base for treatment selection. However, studies are needed to clarify the mechanisms that underlie various types of fatigue, understand the epidemiology of the symptom, and provide an evidence base for management decisions.

Keywords:   fatigue assessment, chronic illness, pain research, pathophysiology

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