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Cancer Epidemiology and Prevention$
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David Schottenfeld and Joseph F. Fraumeni

Print publication date: 2006

Print ISBN-13: 9780195149616

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780195149616.001.0001

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(p.217) 13 Tobacco
Cancer Epidemiology and Prevention



Oxford University Press

This chapter considers the factors that transformed tobacco use from a ceremonial practice in pre-Columbian times to a global epidemic. It discusses the role of nicotine addiction in sustaining and modifying exposure to the carcinogens in tobacco, the cancers caused by various forms of tobacco use, the global burden of tobacco-attributable disease, the extent to which design changes in cigarettes have altered their pathogenicity, the influence of genetic and other factors on susceptibility to addiction or carcinogenesis, and finally the immense opportunities for prevention.

Keywords:   nicotine addiction, cancer, tobacco use, economic burden, cancer prevention

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