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Cancer Epidemiology and Prevention$
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David Schottenfeld and Joseph F. Fraumeni

Print publication date: 2006

Print ISBN-13: 9780195149616

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780195149616.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 16 April 2021

Genetic Modifiers of Cancer Risk

Genetic Modifiers of Cancer Risk

(p.577) 29 Genetic Modifiers of Cancer Risk
Cancer Epidemiology and Prevention


Oxford University Press

This chapter discusses genetic modifiers of cancer risk. Topics covered include rationale for the study of low-penetrance genes, the role of low-penetrance genes in cancer susceptibility, methodological issues, gene selection in population studies, overview of candidate genes, overview of cancer-specific associations, and gene-environment interaction.

Keywords:   cancer susceptibility, low-penetrance genes, gene selection, candidate genes, gene-environment interaction

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