The Microbial Models of Molecular Biology: From Genes to Genomes
Rowland H. Davis
Abstract
This book explains the role of simple biological model systems in the growth of molecular biology. Essentially, the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models — Paramecium and Chlamydomonas, primarily — and the move into eukaryotes with the fungal systems Neurospora, Aspergillus, and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the trans ... More
This book explains the role of simple biological model systems in the growth of molecular biology. Essentially, the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models — Paramecium and Chlamydomonas, primarily — and the move into eukaryotes with the fungal systems Neurospora, Aspergillus, and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the transition to a new model over time, and remnant communities of investigators continue to pursue questions in all these models, as the cutting edge of molecular biological research flows onward from model to model, and onward into higher organisms and, ultimately, mouse and man.
Keywords:
microbial models,
molecular biology,
biological model systems,
bacteriophages,
E. coli,
prokaryotic systems,
algal models,
Paramecium,
Chlamydomonas,
eukaryotes
Bibliographic Information
Print publication date: 2003 |
Print ISBN-13: 9780195154368 |
Published to Oxford Scholarship Online: April 2010 |
DOI:10.1093/acprof:oso/9780195154368.001.0001 |