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The Behavior of the Laboratory RatA Handbook with Tests$
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Ian Q. Whishaw and Bryan Kolb

Print publication date: 2004

Print ISBN-13: 9780195162851

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195162851.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 22 October 2021



(p.236) 22 Stress
The Behavior of the Laboratory Rat

Jaap M. Koolhaas

Sietse F. de Boer

Bauke Buwalda

Oxford University Press

This chapter examines stress models in the rat using the biology of the rat and its natural defense mechanisms as a starting point. It focuses on tests that explore the capacity of rats to cope with ecologically relevant problems. Stress models challenge the natural defense mechanisms and hence call on the adaptive capacity of the animal. However, rather than pushing the animal toward a stress physiological ceiling, it might be far more informative to explore the natural factors that determine and modulate the individual adaptive capacity. These factors include not only perinatal and adult (social) experience but also factors that affect the speed of recovery after a stressor.

Keywords:   laboratory rats, stress models, stress response, defence mechanisms, ecology, adaptive capacity

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