Attention, Genes, and Developmental Disorders
Kim Cornish and John Wilding
Abstract
What is attention? How does it go wrong? Do attention deficits arise from genes or from the environment? Can we cure it with drugs or training? Are there disorders of attention other than deficit disorders? The past decade has seen a burgeoning of research on the subject of attention. This research has been facilitated by advances on several fronts: New methods are now available for viewing brain activity in real time, there is expanding information on the complexities of the biochemistry of neural activity, individual genes can be isolated and their functions identified, analysis of the compo ... More
What is attention? How does it go wrong? Do attention deficits arise from genes or from the environment? Can we cure it with drugs or training? Are there disorders of attention other than deficit disorders? The past decade has seen a burgeoning of research on the subject of attention. This research has been facilitated by advances on several fronts: New methods are now available for viewing brain activity in real time, there is expanding information on the complexities of the biochemistry of neural activity, individual genes can be isolated and their functions identified, analysis of the component processes included under the broad umbrella of “attention” has become increasingly sophisticated, and ingenious methods have been devised for measuring typical and atypical development of these processes, from infancy into childhood, and then into adulthood. This book is concerned with attention and its development, both typical and atypical, particularly in disorders with a known genetic etiology or assumed genetic linkage. Tremendous advances across seemingly diverse disciplines — molecular genetics, pediatric neurology, child psychiatry, developmental cognitive neuroscience, and education s— have culminated in a wealth of new methods for elucidating disorders at multiple levels, possibly paving the way for new treatment options. The book uses three specific-yet-interlinking levels of analysis: genetic blueprint (genotype), the developing brain, and the behavioral-cognitive outcomes (phenotype), as the basis for charting the attention profiles of six well-documented neurodevelopmental disorders: ADHD, autism, fragile X syndrome, Down syndrome, Williams syndrome, and 22q11 deletion syndrome.
Keywords:
attention,
attention deficit,
genetic blueprint,
genotype,
behavioral-cognitive outcomes,
phenotype,
ADHD,
autism,
Down syndrome
Bibliographic Information
Print publication date: 2010 |
Print ISBN-13: 9780195179941 |
Published to Oxford Scholarship Online: September 2010 |
DOI:10.1093/acprof:oso/9780195179941.001.0001 |
Authors
Affiliations are at time of print publication.
Kim Cornish, author
McGill University, Montreal, Canada, and Monash University, Melbourne
John Wilding, author
Royal Holloway College, University of London
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