- Title Pages
- Acknowledgments
- List of Abbreviations
- Contributors
- 1 Models of Neurotoxicity Provide Unique Insight into Normal Development
- 2 Cell Proliferation
- 3 Neuronal Migration
- 4 Neuronal Differentiation: From Axons to Synapses
- 5 Cell Death
- 6 Intracellular Pathways of Neuronal Death
- 7 Developmental Disorders and Evolutionary Expectations: Mechanisms of Resilience
- 8 Prenatal Alcohol Exposure and Human Development
- 9 Influence of Alcohol on Structure of the Developing Human Brain
- 10 Prenatal Ethanol Exposure and Fetal Programming: Implications for Endocrine and Immune Development and Long-Term Health
- 11 Early Exposure to Ethanol Affects the Proliferation of Neuronal Precursors
- 12 Effects of Ethanol on the Regulation of Cell Cycle in Neural Stem Cells
- 13 Mechanisms of Ethanol-Induced Alterations in Neuronal Migration
- 14 Effects of Ethanol on Mechanisms Regulating Neuronal Process Outgrowth
- 15 Neuronal Survival is Compromised by Ethanol: Extracellular Mediators
- 16 Intracellular Events in Ethanol-induced Neuronal Death
- 17 Neural Crest and Developmental Exposure to Ethanol
- 18 Glial Targets of Developmental Exposure to Ethanol
- 19 Tobacco Use During Pregnancy: Epidemiology and Effects on Offspring
- 20 Prenatal Nicotine Exposure and Animal Behavior
- 21 Neuronal Receptors for Nicotine: Functional Diversity and Developmental Changes
- 22 Neural Precursors as Preferential Targets for Drug Abuse: Long-Term Consequences and Latent Susceptibility to Central Nervous System Disorders
- 23 Nicotinic Receptor Regulation of Developing Catecholamine Systems
- Index
Intracellular Events in Ethanol-induced Neuronal Death
Intracellular Events in Ethanol-induced Neuronal Death
- Chapter:
- (p.267) 16 Intracellular Events in Ethanol-induced Neuronal Death
- Source:
- Brain Development
- Author(s):
Sandra M. Mooney
Michael W. Miller
George I. Henderson
- Publisher:
- Oxford University Press
Developmental exposure to ethanol can significantly reduce the number of neurons in specific areas of the brain, resulting in a decrease in the additive processes of cell generation and migration and/or an increase in the substractive process of cell death. This chapter examines the effects of ethanol on intracellular pathways involved in neuronal death.
Keywords: ethanol exposure, neurons, neuronal death, intracellular pathways
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- Title Pages
- Acknowledgments
- List of Abbreviations
- Contributors
- 1 Models of Neurotoxicity Provide Unique Insight into Normal Development
- 2 Cell Proliferation
- 3 Neuronal Migration
- 4 Neuronal Differentiation: From Axons to Synapses
- 5 Cell Death
- 6 Intracellular Pathways of Neuronal Death
- 7 Developmental Disorders and Evolutionary Expectations: Mechanisms of Resilience
- 8 Prenatal Alcohol Exposure and Human Development
- 9 Influence of Alcohol on Structure of the Developing Human Brain
- 10 Prenatal Ethanol Exposure and Fetal Programming: Implications for Endocrine and Immune Development and Long-Term Health
- 11 Early Exposure to Ethanol Affects the Proliferation of Neuronal Precursors
- 12 Effects of Ethanol on the Regulation of Cell Cycle in Neural Stem Cells
- 13 Mechanisms of Ethanol-Induced Alterations in Neuronal Migration
- 14 Effects of Ethanol on Mechanisms Regulating Neuronal Process Outgrowth
- 15 Neuronal Survival is Compromised by Ethanol: Extracellular Mediators
- 16 Intracellular Events in Ethanol-induced Neuronal Death
- 17 Neural Crest and Developmental Exposure to Ethanol
- 18 Glial Targets of Developmental Exposure to Ethanol
- 19 Tobacco Use During Pregnancy: Epidemiology and Effects on Offspring
- 20 Prenatal Nicotine Exposure and Animal Behavior
- 21 Neuronal Receptors for Nicotine: Functional Diversity and Developmental Changes
- 22 Neural Precursors as Preferential Targets for Drug Abuse: Long-Term Consequences and Latent Susceptibility to Central Nervous System Disorders
- 23 Nicotinic Receptor Regulation of Developing Catecholamine Systems
- Index
