- Title Pages
- Acknowledgments
- List of Abbreviations
- Contributors
- 1 Models of Neurotoxicity Provide Unique Insight into Normal Development
- 2 Cell Proliferation
- 3 Neuronal Migration
- 4 Neuronal Differentiation: From Axons to Synapses
- 5 Cell Death
- 6 Intracellular Pathways of Neuronal Death
- 7 Developmental Disorders and Evolutionary Expectations: Mechanisms of Resilience
- 8 Prenatal Alcohol Exposure and Human Development
- 9 Influence of Alcohol on Structure of the Developing Human Brain
- 10 Prenatal Ethanol Exposure and Fetal Programming: Implications for Endocrine and Immune Development and Long-Term Health
- 11 Early Exposure to Ethanol Affects the Proliferation of Neuronal Precursors
- 12 Effects of Ethanol on the Regulation of Cell Cycle in Neural Stem Cells
- 13 Mechanisms of Ethanol-Induced Alterations in Neuronal Migration
- 14 Effects of Ethanol on Mechanisms Regulating Neuronal Process Outgrowth
- 15 Neuronal Survival is Compromised by Ethanol: Extracellular Mediators
- 16 Intracellular Events in Ethanol-induced Neuronal Death
- 17 Neural Crest and Developmental Exposure to Ethanol
- 18 Glial Targets of Developmental Exposure to Ethanol
- 19 Tobacco Use During Pregnancy: Epidemiology and Effects on Offspring
- 20 Prenatal Nicotine Exposure and Animal Behavior
- 21 Neuronal Receptors for Nicotine: Functional Diversity and Developmental Changes
- 22 Neural Precursors as Preferential Targets for Drug Abuse: Long-Term Consequences and Latent Susceptibility to Central Nervous System Disorders
- 23 Nicotinic Receptor Regulation of Developing Catecholamine Systems
- Index
Intracellular Pathways of Neuronal Death
Intracellular Pathways of Neuronal Death
- Chapter:
- (p.91) 6 Intracellular Pathways of Neuronal Death
- Source:
- Brain Development
- Author(s):
Sandra M. Mooney
George I. Henderson
- Publisher:
- Oxford University Press
Neuronal death is essential for normal development of the central nervous system. Without it, the nervous system can become overpopulated with poorly integrated neurons and circuitry that produces functional deficits. This chapter considers in vitro and in vivo studies of neuronal death.
Keywords: neurons, neuronal death, functional deficits, central nervous system
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- Title Pages
- Acknowledgments
- List of Abbreviations
- Contributors
- 1 Models of Neurotoxicity Provide Unique Insight into Normal Development
- 2 Cell Proliferation
- 3 Neuronal Migration
- 4 Neuronal Differentiation: From Axons to Synapses
- 5 Cell Death
- 6 Intracellular Pathways of Neuronal Death
- 7 Developmental Disorders and Evolutionary Expectations: Mechanisms of Resilience
- 8 Prenatal Alcohol Exposure and Human Development
- 9 Influence of Alcohol on Structure of the Developing Human Brain
- 10 Prenatal Ethanol Exposure and Fetal Programming: Implications for Endocrine and Immune Development and Long-Term Health
- 11 Early Exposure to Ethanol Affects the Proliferation of Neuronal Precursors
- 12 Effects of Ethanol on the Regulation of Cell Cycle in Neural Stem Cells
- 13 Mechanisms of Ethanol-Induced Alterations in Neuronal Migration
- 14 Effects of Ethanol on Mechanisms Regulating Neuronal Process Outgrowth
- 15 Neuronal Survival is Compromised by Ethanol: Extracellular Mediators
- 16 Intracellular Events in Ethanol-induced Neuronal Death
- 17 Neural Crest and Developmental Exposure to Ethanol
- 18 Glial Targets of Developmental Exposure to Ethanol
- 19 Tobacco Use During Pregnancy: Epidemiology and Effects on Offspring
- 20 Prenatal Nicotine Exposure and Animal Behavior
- 21 Neuronal Receptors for Nicotine: Functional Diversity and Developmental Changes
- 22 Neural Precursors as Preferential Targets for Drug Abuse: Long-Term Consequences and Latent Susceptibility to Central Nervous System Disorders
- 23 Nicotinic Receptor Regulation of Developing Catecholamine Systems
- Index
