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Brain DevelopmentNormal Processes and the Effects of Alcohol and Nicotine$
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Michael W. Miller

Print publication date: 2006

Print ISBN-13: 9780195183139

Published to Oxford Scholarship Online: January 2010

DOI: 10.1093/acprof:oso/9780195183139.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 18 October 2021

Influence of Alcohol on Structure of the Developing Human Brain

Influence of Alcohol on Structure of the Developing Human Brain

(p.143) 9 Influence of Alcohol on Structure of the Developing Human Brain
Brain Development

Susanna L. Fryer

Christie L. McGee

Andrea D. Spadoni

Edward P. Riley

Oxford University Press

This chapter discusses the brain structural changes arising from fetal alcohol exposure. It argues that teratogenic exposure to alcohol causes permanent changes in brain structure and differentially affects specific components and regions of the brain. These structural changes likely underlie deficits in the cognitive ability and adaptive functioning of exposed individuals. Structural brain deficits revealed by quantitative image analyses of alcohol-exposed individuals include reductions in overall brain volume and alterations in brain shape, density, and bilateral symmetry.

Keywords:   fetal alcohol exposure, brain structure, bilateral symmetry, teratogenic exposure

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