- Title Pages
- Preface
- Introduction
-
Chapter 1 The Developing Brain and Adolescent-Typical Behavior Patterns -
Chapter 2 Competence, Resilience, and Development in Adolescence -
Chapter 3 Mapping Adolescent Brain Maturation Using Structural Magnetic Resonance Imaging -
Chapter 4 The Metamorphosis -
Chapter 5 Transcriptional Regulation in Schizophrenia -
Chapter 6 Stress Effects on the Developing Brain -
Chapter 7 Maternal Programming of Defensive Responses Through Sustained Effects on Gene Expression -
Chapter 8 Neuropeptides and the Development of Social Behaviors -
Chapter 9 The Effects of Early Deprivation on Brain-Behavioral Development -
Chapter 10 Social Stress, Affect, and Neural Function in Adolescence -
Chapter 11 Stress-Induced Pathophysiology Within the Schizophrenia Patient Brain -
Chapter 12 Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence -
Chapter 13 The Adolescent Surge in Depression and Emergence of Gender Differences -
Chapter 14 Early Identification and Prevention of Early-Onset Bipolar Disorder -
Chapter 15 Resilience and Vulnerability to Trauma -
Chapter 16 The Developing Adolescent Brain in Socioeconomic Context -
Chapter 17 Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction -
Chapter 18 Modifying Brain Networks Underlying Self-Regulation -
Chapter 19 The BrainWise Curriculum -
Chapter 20 The Role of Preventive Interventions in Enhancing Neurocognitive Functioning and Promoting Competence in Adolescence - Conclusions
- Appendix A
- Appendix B
- Appendix C
- Index
- Plates
Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction
Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction
- Chapter:
- (p.388) Chapter 17 Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction
- Source:
- Adolescent Psychopathology and the Developing Brain
- Author(s):
Charles P. O’Brien
- Publisher:
- Oxford University Press
This chapter reviews the deleterious effects of addictive drugs on brain development and what is known about ways to reverse these effects. It shows that adolescence is a vulnerable period for initiating substance abuse. Progression from use to abuse to addiction is influenced by multiple, simultaneous variables categorized in the medical model as agent, host, and environment. However, the majority of adolescents who experiment with drugs do not progress to addiction, although they could experience harm or fatalities from acute effects and accidents. Those beginning at a younger age have the highest risk of developing an addiction and the poorest results when they later seek treatment as adults.
Keywords: addiction risk, adolescent vulnerability, adolescent brain development, substance use
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- Title Pages
- Preface
- Introduction
-
Chapter 1 The Developing Brain and Adolescent-Typical Behavior Patterns -
Chapter 2 Competence, Resilience, and Development in Adolescence -
Chapter 3 Mapping Adolescent Brain Maturation Using Structural Magnetic Resonance Imaging -
Chapter 4 The Metamorphosis -
Chapter 5 Transcriptional Regulation in Schizophrenia -
Chapter 6 Stress Effects on the Developing Brain -
Chapter 7 Maternal Programming of Defensive Responses Through Sustained Effects on Gene Expression -
Chapter 8 Neuropeptides and the Development of Social Behaviors -
Chapter 9 The Effects of Early Deprivation on Brain-Behavioral Development -
Chapter 10 Social Stress, Affect, and Neural Function in Adolescence -
Chapter 11 Stress-Induced Pathophysiology Within the Schizophrenia Patient Brain -
Chapter 12 Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence -
Chapter 13 The Adolescent Surge in Depression and Emergence of Gender Differences -
Chapter 14 Early Identification and Prevention of Early-Onset Bipolar Disorder -
Chapter 15 Resilience and Vulnerability to Trauma -
Chapter 16 The Developing Adolescent Brain in Socioeconomic Context -
Chapter 17 Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction -
Chapter 18 Modifying Brain Networks Underlying Self-Regulation -
Chapter 19 The BrainWise Curriculum -
Chapter 20 The Role of Preventive Interventions in Enhancing Neurocognitive Functioning and Promoting Competence in Adolescence - Conclusions
- Appendix A
- Appendix B
- Appendix C
- Index
- Plates
