- Title Pages
- Preface
- Introduction
-
Chapter 1 The Developing Brain and Adolescent-Typical Behavior Patterns -
Chapter 2 Competence, Resilience, and Development in Adolescence -
Chapter 3 Mapping Adolescent Brain Maturation Using Structural Magnetic Resonance Imaging -
Chapter 4 The Metamorphosis -
Chapter 5 Transcriptional Regulation in Schizophrenia -
Chapter 6 Stress Effects on the Developing Brain -
Chapter 7 Maternal Programming of Defensive Responses Through Sustained Effects on Gene Expression -
Chapter 8 Neuropeptides and the Development of Social Behaviors -
Chapter 9 The Effects of Early Deprivation on Brain-Behavioral Development -
Chapter 10 Social Stress, Affect, and Neural Function in Adolescence -
Chapter 11 Stress-Induced Pathophysiology Within the Schizophrenia Patient Brain -
Chapter 12 Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence -
Chapter 13 The Adolescent Surge in Depression and Emergence of Gender Differences -
Chapter 14 Early Identification and Prevention of Early-Onset Bipolar Disorder -
Chapter 15 Resilience and Vulnerability to Trauma -
Chapter 16 The Developing Adolescent Brain in Socioeconomic Context -
Chapter 17 Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction -
Chapter 18 Modifying Brain Networks Underlying Self-Regulation -
Chapter 19 The BrainWise Curriculum -
Chapter 20 The Role of Preventive Interventions in Enhancing Neurocognitive Functioning and Promoting Competence in Adolescence - Conclusions
- Appendix A
- Appendix B
- Appendix C
- Index
- Plates
Maternal Programming of Defensive Responses Through Sustained Effects on Gene Expression
Maternal Programming of Defensive Responses Through Sustained Effects on Gene Expression
- Chapter:
- (p.148) Chapter 7 Maternal Programming of Defensive Responses Through Sustained Effects on Gene Expression
- Source:
- Adolescent Psychopathology and the Developing Brain
- Author(s):
Michael J. Meaney
- Publisher:
- Oxford University Press
This chapter provides an overview of the long-term effects of early stress on the subsequent development of both physical and mental disorder. It then discusses the role of maternal care during pre- and postnatal periods as an early source of these effects, using research conducted in the laboratory with the rat. The chapter then reviews potential mediators of the effects of maternal behavior on gene expression. The chapter concludes with the questions that remain regarding the effects of early stress on pathology.
Keywords: stress response, physical disorder, mental disorder, prenatal period, postnatal period, maternal behavior, gene expression
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- Title Pages
- Preface
- Introduction
-
Chapter 1 The Developing Brain and Adolescent-Typical Behavior Patterns -
Chapter 2 Competence, Resilience, and Development in Adolescence -
Chapter 3 Mapping Adolescent Brain Maturation Using Structural Magnetic Resonance Imaging -
Chapter 4 The Metamorphosis -
Chapter 5 Transcriptional Regulation in Schizophrenia -
Chapter 6 Stress Effects on the Developing Brain -
Chapter 7 Maternal Programming of Defensive Responses Through Sustained Effects on Gene Expression -
Chapter 8 Neuropeptides and the Development of Social Behaviors -
Chapter 9 The Effects of Early Deprivation on Brain-Behavioral Development -
Chapter 10 Social Stress, Affect, and Neural Function in Adolescence -
Chapter 11 Stress-Induced Pathophysiology Within the Schizophrenia Patient Brain -
Chapter 12 Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence -
Chapter 13 The Adolescent Surge in Depression and Emergence of Gender Differences -
Chapter 14 Early Identification and Prevention of Early-Onset Bipolar Disorder -
Chapter 15 Resilience and Vulnerability to Trauma -
Chapter 16 The Developing Adolescent Brain in Socioeconomic Context -
Chapter 17 Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction -
Chapter 18 Modifying Brain Networks Underlying Self-Regulation -
Chapter 19 The BrainWise Curriculum -
Chapter 20 The Role of Preventive Interventions in Enhancing Neurocognitive Functioning and Promoting Competence in Adolescence - Conclusions
- Appendix A
- Appendix B
- Appendix C
- Index
- Plates
