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Neurovascular Medicine – Pursuing Cellular Longevity for Healthy Aging - Oxford Scholarship Online
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Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Kenneth Maiese


Disorders of the nervous and vascular systems continue to burden the planet's population not only with increasing morbidity and mortality, but also with a significant financial drain through increasing medical care costs coupled to a progressive loss in economic productivity. For example, more than 500 million individuals suffer from nervous and vascular system disorders in the world that comprise both acute and chronic degenerative diseases such as hypertension, cardiac insufficiency, diabetes mellitus, stroke, traumatic brain injury, and Alzheimer's disease. Given the vulnerability of the ne ... More

Keywords: nervous system, vascular system, degenerative diseases, cellular pathways, cellular function, longevity, inflammatory cells, cell biology, healthy aging

Bibliographic Information

Print publication date: 2009 Print ISBN-13: 9780195326697
Published to Oxford Scholarship Online: January 2010 DOI:10.1093/acprof:oso/9780195326697.001.0001


Affiliations are at time of print publication.

Kenneth Maiese, editor
Wayne State University

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Part I Unraveling Pathways of Clinical Function and Disability

Chapter 1 Role of Prion Protein During Normal Physiology and Disease

Adriana Simon Coitinho, and Glaucia N. M. Hajj

Chapter 4 Retinal Cellular Metabolism and its Regulation and Control

Dao-Yi Yu, Stephen J Cringle, Paula K Yu, Er-Ning Su, Xinghuai Sun, Wenyi Guo, William H Morgan, Xiao-Bo Yu, and Chandrakumar Balaratnasingam

Part II The Potential of Stem and Progenitor Cell Applications for Degenerative Disorders

Chapter 11 Glutamatergic Signaling In Neurogenesis

Noritaka Nakamichi, and Yukio Yoneda

Part III Elucidating Inflammatory Mediators of Disease

Chapter 13 Brain Inflammation and the Neuronal Fate: from Neurogenesis to Neurodegeneration

Maria Antonietta Ajmone-Cat, Emanuele Cacci, and Luisa Minghetti

Part IV Translating Novel Cellular Pathways into Viable Therapeutic Strategies

Chapter 17 Neurobiology of Postischemic Recuperation in the Aged Mammalian Brain

Aurel Popa-Wagner, Adrian Balseanu, Leon Zagrean, Imtiaz M. Shah, Mario Di Napoli, Henrik Ahlenius, and Zaal Kokaia

Chapter 19 Redox Signaling and Vascular Function

J. Will Langston, Magdalena L. Circu, and Tak Yee Aw

Chapter 20 Gene Therapy Toward Clinical Application in the Cardiovascular Field

Hironori Nakagami, Mariana Kiomy Osako, and Ryuichi Morishita

End Matter