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Neuroimaging in Epilepsy$
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Harry Chugani, MD

Print publication date: 2010

Print ISBN-13: 9780195342765

Published to Oxford Scholarship Online: January 2011

DOI: 10.1093/acprof:oso/9780195342765.001.0001

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Functional MRI

Functional MRI

(p.77) Chapter 5 Functional MRI
Neuroimaging in Epilepsy

William Davis Gaillard

Oxford University Press

Functional Imaging with MRI using BOLD techniques plays an increasing role in clinical practice. fMRI may be used for interictal source localization but is more commonly used to identify eloquent areas to be spared during epilepsy surgery. fMRI is used to identify primary sensory cortex –visual, sensory, and auditory and to identify motor cortex. There are several language paradigms that may be used to identify frontal (“expressive”) and temporal (“receptive”) speech. These methods have excellent agreement with Wada and predict post operative naming outcomes. There are circumstances in which fMRI is not helpful as the BOLD response may be disrupted by several pathological processes. fMRI memory tasks have good agreement with Wada, demonstrate material specificity, show functional capacity to be more important than functional reserve, and may predict outcomes of specific memory tasks.

Keywords:   fMRI, epilepsy, language, memory, source localization

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