- Title Pages
- Dedication
- Preface
- Acknowledgments
- I.1 Fundamentals of Electricity
- I.2 Patch-Clamp Recording
- I.3 Physical Basis for the Resting Potential
- I.4 Basis of the Nerve Impulse
- I.5 Properties of Neurons
- I.6 Electrophysiology of Neuronal Interactions
- I.7 Neuronal Oscillators
- SECTION II DESCRIPTION OF THE MODELS
- II.1 Electricity Model
- II.2 Patch Model
- II.3 Soma Model
- II.4 Axon Models
- II.5 Neuron Model
- II.6 Synapse Model
- II.7 Circuit Model
- II.8 Stimulator Control
- SECTION III EQUATIONS UNDERLYING NEURODYNAMIX II SIMULATIONS
- III.1 Equations Underlying the Electricity Model
- III.2 Equations Underlying the Patch Model
- III.3 Equations Underlying the Soma Model
- III.4 Equations Underlying the Axon Models
- III.5 Equations Underlying the Neuron Model
- III.6 Equations Underlying the Synapse Model
- III.7 Equations Underlying the Circuit Model
- IV.1 Form of the Equations
- IV.2 Numerical Solution
- Guide to <i>NeuroDynamix II</i> Software
- Bibliography
- Index
Axon Models
Axon Models
- Chapter:
- (p.157) II.4 Axon Models
- Source:
- NeuroDynamix II
- Author(s):
W. Otto Friesen
Jonathon A. Friesen
- Publisher:
- Oxford University Press
The Axon model simulates the equations and parameters derived from experiments by Hodgkin and Huxley on the squid giant axon. Because of the exact correspondence between the equations incorporated into this model and the equations developed in the studies of Hodgkin and Huxley, this model generates graphs that mirror precisely the theoretical curves depicted in the Hodgkin-Huxley papers on the squid axon. Three similar models are included in this chapter: the single space-clamped axon, simultaneous simulations of several spaced-clamped axons to compare model output when parameters are altered, and a simulation of the spatially extended axon to illustrate impulse propagation.
Keywords: parameter, variable, axon, voltage clamp, ionic currents, activation, inactivation, parallel conductance model, action potential, conduction velocity
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- Title Pages
- Dedication
- Preface
- Acknowledgments
- I.1 Fundamentals of Electricity
- I.2 Patch-Clamp Recording
- I.3 Physical Basis for the Resting Potential
- I.4 Basis of the Nerve Impulse
- I.5 Properties of Neurons
- I.6 Electrophysiology of Neuronal Interactions
- I.7 Neuronal Oscillators
- SECTION II DESCRIPTION OF THE MODELS
- II.1 Electricity Model
- II.2 Patch Model
- II.3 Soma Model
- II.4 Axon Models
- II.5 Neuron Model
- II.6 Synapse Model
- II.7 Circuit Model
- II.8 Stimulator Control
- SECTION III EQUATIONS UNDERLYING NEURODYNAMIX II SIMULATIONS
- III.1 Equations Underlying the Electricity Model
- III.2 Equations Underlying the Patch Model
- III.3 Equations Underlying the Soma Model
- III.4 Equations Underlying the Axon Models
- III.5 Equations Underlying the Neuron Model
- III.6 Equations Underlying the Synapse Model
- III.7 Equations Underlying the Circuit Model
- IV.1 Form of the Equations
- IV.2 Numerical Solution
- Guide to <i>NeuroDynamix II</i> Software
- Bibliography
- Index