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NeuroDynamix IIConcepts of Neurophysiology Illustrated by Computer Simulations$
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W. Otto Friesen and Jonathon Friesen

Print publication date: 2009

Print ISBN-13: 9780195371833

Published to Oxford Scholarship Online: February 2010

DOI: 10.1093/acprof:oso/9780195371833.001.0001

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Axon Models

Axon Models

(p.157) II.4 Axon Models
NeuroDynamix II

W. Otto Friesen

Jonathon A. Friesen

Oxford University Press

The Axon model simulates the equations and parameters derived from experiments by Hodgkin and Huxley on the squid giant axon. Because of the exact correspondence between the equations incorporated into this model and the equations developed in the studies of Hodgkin and Huxley, this model generates graphs that mirror precisely the theoretical curves depicted in the Hodgkin-Huxley papers on the squid axon. Three similar models are included in this chapter: the single space-clamped axon, simultaneous simulations of several spaced-clamped axons to compare model output when parameters are altered, and a simulation of the spatially extended axon to illustrate impulse propagation.

Keywords:   parameter, variable, axon, voltage clamp, ionic currents, activation, inactivation, parallel conductance model, action potential, conduction velocity

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