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Integrative Neuroscience and Personalized Medicine - Oxford Scholarship Online
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Integrative Neuroscience and Personalized Medicine

Evian Gordon, MD, PhD and Stephen Koslow, PhD


Key thoughts leaders and practitioners in personalized medicine distil its current status, future directions, and recommendation for successful implementation of for brain disorders. This text is a summary of the “science to patient” continuum in and integrative neuroscience. Included are measures of genes using whole genome approaches and SNIPS, as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. The chapters provide a review of relevant literature; show the personalized diagnostic and treatment predi ... More

Keywords: personalized medicine, integrative neuroscience, healthcare, brain disorders, psychiatric disorders, neurological disorders, mental health, cognition, genomics, standardized methods

Bibliographic Information

Print publication date: 2010 Print ISBN-13: 9780195393804
Published to Oxford Scholarship Online: January 2011 DOI:10.1093/acprof:oso/9780195393804.001.0001


Affiliations are at time of print publication.

Evian Gordon, MD, PhD, editor

Stephen Koslow, PhD, editor

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Section 1 Genesis of Personalized Medicine

1 The History of Personalized Medicine

Edward Abrahams, PhD and Mike Silver, PhD

Section 2 Personalized Medicine and Mental Disorders

5 Stress and the Impact of Personalized Medicine

Charles F. Gillespie, MD, PhD, Elisabeth B. Binder, MD, PhD, Paul E. Holtzheimer, MD, and Charles B. Nemeroff, MD, PhD

6 Personalized Medicine for Schizophrenia

Jacob S. Ballon, MD, Ragy R. Girgis, MD, and Jeffrey A. Lieberman, MD

Section 3 Personalized Medicine and Other Brain Disorders

8 The Role of Neuroimaging Biomarkers in Personalized Medicine for Neurodegenerative and Psychiatric Disorders

Ellen M. Migo, PhD, Steve C.R. Williams, PhD, William R. Crum, DPhil, Matthew J. Kempton, PhD, and Ulrich Ettinger, PhD

Theranostics and Translation toward Personalized Medicine for Multiple Sclerosis

Ariel Miller, MD, PhD, Tamar Paperna, PhD,Opher Caspi, MD, PhD, Izabella Lejbkowicz, PhD,Elsebeth Staun-Ram, PhD, and Nili Avidan, PhD

Section 4 Personalized Medicine and Health Care

14 Economic Impacts of the Personalized Medicine Tsunami

Dan Segal, MSc and David E. Williams, MBA

Section 5 Conclusion and Recommendations

15 Accelerating the Future of Personalized Medicine

Evian Gordon, PhD, MBBCH and Stephen H. Koslow, PhD