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Human Genome Epidemiology, 2nd EditionBuilding the evidence for using genetic information to improve health and prevent disease$
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Muin Khoury, Sara Bedrosian, Marta Gwinn, Julian Higgins, John Ioannidis, and Julian Little

Print publication date: 2009

Print ISBN-13: 9780195398441

Published to Oxford Scholarship Online: May 2010

DOI: 10.1093/acprof:oso/9780195398441.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 11 August 2020

STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

(p.188) 10 STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement
Human Genome Epidemiology, 2nd Edition

Julian Little

Julian P. T. Higgins

John P. A. Ioannidis

David Moher

France Gagnon

Erik von Elm

Muin J. Khoury

Barbara Cohen

George Davey Smith

Jeremy Grimshaw

Paul Scheet

Marta Gwinn

Robin E. Williamson

Guang Yong Zou

Kimberley Hutchings

Candice Y. Johnson

Valerie Tait

Miriam Wiens

Jean Golding

Cornelia M. van Duijn

John McLaughlin

Andrew Paterson

George Wells

Isabel Fortier

Matthew Freedman

Maja Zecevic

Richard A. King

Claire Infante-Rivard

Alexandre Stewart

Nick Birkett

Oxford University Press

This chapter proposes and justifies a set of guiding principles for reporting results of genetic association studies. The epidemiology community has recently developed the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) Statement for cross-sectional, case-control, and cohort studies. Given the relevance of general epidemiologic principles for genetic association studies, recommendations are proposed in an extension of the STROBE Statement called the STrengthening the REporting of Genetic Association studies (STREGA) Statement. The recommendations of the STROBE Statement have a strong foundation because they are based on empirical evidence on the reporting of observational studies, and because they involved extensive consultations in the epidemiologic research community.

Keywords:   gene associations, STREGA, case-control studies, cross-sectional studies

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