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The Parahippocampal Region – Organization and Role in Cognitive Function - Oxford Scholarship Online
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The Parahippocampal Region: Organization and Role in Cognitive Function

Menno Witter and Floris Wouterlood


Advances in imaging technologies have enabled researchers to build on the evidence obtained from lesion and behavioural studies to propose a range of functions for the parahippocampal region. It is now possible to image the region in healthy human subjects and to define the pathological changes occurring during the early phases of a range of neurologic and psychiatric conditions. The results have uncovered evidence suggesting that the region plays an important role in the higher cognitive processes of learning and memory, and in specific brain diseases, including Alzheimer's disease, schizophr ... More

Keywords: imaging technologies, lesion studies, behavioural studies, parahippocampal region, pathological changes, schizophrenia, epilepsy, aging, memory, perception

Bibliographic Information

Print publication date: 2002 Print ISBN-13: 9780198509172
Published to Oxford Scholarship Online: March 2012 DOI:10.1093/acprof:oso/9780198509172.001.0001


Affiliations are at time of print publication.

Menno Witter, editor

Floris Wouterlood, editor
both at the Department of Anatomy, Vrije University Medical Center, Amsterdam, The Netherlands

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Section 1

2 Postnatal development of the human entorhinal cortex

L. Graterón, A.M. Insausti, F. García-Bragado, M.M. Arroyo-Jiménez, P. Marcos, A. Martínez-Marcos, X. Blaizot, E. Artacho-Pérula, and R. Insausti

Section 2

Section 3

11 Experimental lesions of the parahippocampal region in rats

Rebecca D. Burwell, David J. Bucci, Kjesten A. Wiig, Michael P. Saddoris, and Matthew R. Sanborn

13 Imaging cognitive function of the parahippocampal region

Guillén Fernández, and Indira Tendolkar

Section 4

15 The parahippocampal region in schizophrenia

Konrad Talbot, and Steven E. Arnold

End Matter