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Neurobiology of Nociceptors - Oxford Scholarship Online
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Neurobiology of Nociceptors

Carlos Belmonte and Fernando Cervero


This is a comprehensive review of all aspects of nociceptor function, including the structure of nociceptor endings, their neurochemistry, and evolutionary considerations. It deals with the functional properties of nociceptors innervating different organs and the biophysical mechanisms underlying the transduction process in nociceptors. There are sections on how nociceptor function is modified by nerve injury and regeneration and on its physiopathology.

Keywords: nociceptor function, nociceptor endings, neurochemistry, functional properties, nociceptors, biophysical mechanisms, transduction, nerve injury, regeneration, physiopathology

Bibliographic Information

Print publication date: 1996 Print ISBN-13: 9780198523345
Published to Oxford Scholarship Online: March 2012 DOI:10.1093/acprof:oso/9780198523345.001.0001


Affiliations are at time of print publication.

Carlos Belmonte, editor
University of Alicante

Fernando Cervero, editor
University of Alcala de Henares

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Part 1 Basic aspects of nociceptor function

2 Structure of nociceptor ‘endings’

Kruger Lawrence, and Halata Zdenek

Part 2 Nociceptors and the signalling of injury

5 Cutaneous nociceptors

Campbell James N., and Meyer Richard A.

6 Corneal nociceptors

Belmonte Carlos, and Gallar Juana

8 Neurobiology of articular nociceptors

Schaible Hans-Georg, and Schmidt Robert F.

9 Visceral nociceptors

Cervero Fernando

Part 3 Transduction mechanisms and sensitization

Part 4 Functions of nociceptors

15 Neural mechanisms of primary hyperalgesia

Meyer Richard A., Raja Srinivasa N., and Campbell James N.

Part 5 Nociceptor plasticity

21 Pathophysiology of human nociceptor function

Ochoa JosÈ L., Serra Jordi, and Campero Mario

End Matter