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Brain Damage, Brain Repair$
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James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

Print publication date: 2002

Print ISBN-13: 9780198523376

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198523376.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 05 March 2021

Peripheral nerve regeneration

Peripheral nerve regeneration

(p.145) 11 Peripheral nerve regeneration
Brain Damage, Brain Repair

James W. Fawcett

Anne E. Rosser

Stephen B. Dunnett

Oxford University Press

Mammals have retained the ability to regenerate axons in the peripheral nervous system (PNS) and, if properly treated, can regain much of the function that is lost after peripheral nerve damage. Not only do the axons regenerate in the periphery, but they restore functional motor connections with muscles, and functional sensory connections with the skin. Nevertheless, peripheral nerve repair is seldom perfect, due both to problems of axon guidance and to other factors that can limit regeneration. There are, therefore, several problems that need to be solved before a regenerated peripheral nerve can completely restore normal function.

Keywords:   nerve regeneration, axons, peripheral nervous system, peripheral nerve damage, functional motor connections, functional sensory connections

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