- Title Pages
- Dedication
- Contributors
- Abbreviations
- 1 Death and survival in the nervous system
- 2 Axotomy and mechanical damage
- 3 Metabolic damage
- 4 Inflammation and demyelination
- 5 Infection
- 6 Neurodegenerative disease
- 7 Neuroprotection
- 8 Steroids
- 9 Trophic factors
- 10 Control of inflammation
- 11 Peripheral nerve regeneration
- 12 Failure of CNS regeneration
- 13 Anatomical plasticity
- 14 Biochemical plasticity
- 15 Remyelination
- 16 Coma
- 17 Motor, sensory, and autonomic function
- 18 Cognition
- 19 Psychiatric assessment
- 20 Pharmacological management
- 21 Neuropsychological rehabilitation
- 22 Axon regeneration in the CNS
- 23 Primary neuronal transplantation
- 24 Glial transplantation
- 25 Stem cells
- 26 Gene therapy
- Appendix 1 Alzheimer's disease
- Appendix 2 Amyotrophic lateral sclerosis (ALS)/Motor neurone disease
- Appendix 3 Creutzfeldt-Jakob disease (CJD)
- Appendix 4 Epilepsy
- Appendix 5 Huntington's disease
- Appendix 6 Multiple sclerosis
- Appendix 7 Parkinson's disease
- Appendix 8 Spinal-cord injury
- Appendix 9 Stroke
- References
- Index
Cognition
Cognition
By Andrew D. Lawrence and Barbara J. Sahakian
- Chapter:
- (p.243) 18 Cognition
- Source:
- Brain Damage, Brain Repair
- Author(s):
James W. Fawcett
Anne E. Rosser
Stephen B. Dunnett
- Publisher:
- Oxford University Press
This chapter aims to outline the role of cognitive testing as an outcome measure in evaluating treatments for dementia, with a particular emphasis on neural transplantation strategies. It begins with a brief overview of issues in the diagnosis of dementia. It then reviews the desirable characteristics of instruments for evaluating dementia treatments, followed by a discussion of one particular battery: that is used in the CAPIT-HD neural transplantation programme, in order to demonstrate the application of the principles of cognitive assessment to a clinical research setting.
Keywords: cognitive testing, dementia, neural transplantation, cognitive assessment, clinical research setting
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- Title Pages
- Dedication
- Contributors
- Abbreviations
- 1 Death and survival in the nervous system
- 2 Axotomy and mechanical damage
- 3 Metabolic damage
- 4 Inflammation and demyelination
- 5 Infection
- 6 Neurodegenerative disease
- 7 Neuroprotection
- 8 Steroids
- 9 Trophic factors
- 10 Control of inflammation
- 11 Peripheral nerve regeneration
- 12 Failure of CNS regeneration
- 13 Anatomical plasticity
- 14 Biochemical plasticity
- 15 Remyelination
- 16 Coma
- 17 Motor, sensory, and autonomic function
- 18 Cognition
- 19 Psychiatric assessment
- 20 Pharmacological management
- 21 Neuropsychological rehabilitation
- 22 Axon regeneration in the CNS
- 23 Primary neuronal transplantation
- 24 Glial transplantation
- 25 Stem cells
- 26 Gene therapy
- Appendix 1 Alzheimer's disease
- Appendix 2 Amyotrophic lateral sclerosis (ALS)/Motor neurone disease
- Appendix 3 Creutzfeldt-Jakob disease (CJD)
- Appendix 4 Epilepsy
- Appendix 5 Huntington's disease
- Appendix 6 Multiple sclerosis
- Appendix 7 Parkinson's disease
- Appendix 8 Spinal-cord injury
- Appendix 9 Stroke
- References
- Index
