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Brain Damage, Brain Repair$
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Brain Damage, Brain Repair

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

Print publication date: 2002

Print ISBN-13: 9780198523376

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198523376.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 05 March 2021

Metabolic damage

Metabolic damage

Chapter:
(p.26) 3 Metabolic damage
Source:
Brain Damage, Brain Repair
Author(s):

James W. Fawcett

Anne E. Rosser

Stephen B. Dunnett

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198523376.003.0003

Many conditions can cause metabolic damage to the CNS, and they do so through a variety of mechanisms. Stroke, for instance, causes anoxic damage to a region of the brain, the actual cell death being due to excitotoxicity, release of free radicals, release of nitric oxide, and other mechanisms. This chapter therefore describes some of the major mechanisms causing metabolic damage in CNS pathology, and then some of the more common conditions.

Keywords:   metabolic damage, CNS, stroke, anoxic damage, cell death, nitric oxide

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