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Brain Damage, Brain Repair$
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James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

Print publication date: 2002

Print ISBN-13: 9780198523376

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198523376.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 05 March 2021



By Joe Herbert

(p.121) 8 Steroids
Brain Damage, Brain Repair

James W. Fawcett

Anne E. Rosser

Stephen B. Dunnett

Oxford University Press

The adrenal cortex secretes a wide range of steroids. Nearly all attention has been focused on the role in brain damage of cortisol (or corticosterone, its counterpart in some species). Only recently have the powerful effects on neural function of other adrenal-derived steroids been recognised. The secretion of cortisol is highly labile. There are marked diurnal variations: highest levels coincide with the start of activity, irrespective of when that occurs (e.g. in the early morning in humans, but at the start of the night in rats and other nocturnal species).

Keywords:   steroids, adrenal cortex, cortisol, brain damage, diurnal variations, macromolecular receptors

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