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Coronary Heart Disease EpidemiologyFrom aetiology to public health$
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Michael Marmot and Paul Elliott

Print publication date: 2005

Print ISBN-13: 9780198525738

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780198525738.001.0001

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Chronic infection and circulating markers of inflammation

Chronic infection and circulating markers of inflammation

(p.448) Chapter 27 Chronic infection and circulating markers of inflammation
Coronary Heart Disease Epidemiology

P. Whincup

J. Danesh

Oxford University Press

This chapter provides a critical review of the available epidemiological and clinical evidence on CHD and markers of persistent infection and of inflammation. Epidemiological and clinical data on specific persistent infective agents and CHD is generally weak and inconclusive. Although larger and more rigorous studies now suggest that it is unlikely that chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or CMV are strong determinants of CHD, available studies have been unable to confirm or exclude the existence of any modest associations.

Keywords:   coronary heart disease, cardiovascular disease, CHD, persistent infection

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