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Coronary Heart Disease EpidemiologyFrom aetiology to public health$
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Michael Marmot and Paul Elliott

Print publication date: 2005

Print ISBN-13: 9780198525738

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780198525738.001.0001

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The developmental origins of coronary heart disease

The developmental origins of coronary heart disease

(p.547) Chapter 32 The developmental origins of coronary heart disease
Coronary Heart Disease Epidemiology

D. J. P. Barker

Oxford University Press

This chapter discusses the developmental origins of coronary heart disease. The recent discovery that people who develop coronary heart disease (CHD) grew differently to other people during fetal life and childhood has led to a new ‘developmental’ model for the disease. Studies have shown an association between low birthweight and CHD. Low birthweight has also been shown to predict altered glucose tolerance in studies around the world.

Keywords:   coronary heart disease, cardiovascular disease, fetal origins, childhood growth, type 2 diabetes, hypertension

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