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Coronary Heart Disease EpidemiologyFrom aetiology to public health$
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Michael Marmot and Paul Elliott

Print publication date: 2005

Print ISBN-13: 9780198525738

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780198525738.001.0001

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Contributions to change: treatment

Contributions to change: treatment

(p.850) Chapter 49 Contributions to change: treatment
Coronary Heart Disease Epidemiology

H. Tunstall-Pedoe

Oxford University Press

This chapter considers the impact of treatment on cardiovascular disease. It argues that for the first two decades of the last half century, it is unlikely that treatment had much impact on coronary heart disease which followed its own natural history. The development of powerful new pharmacological agents along with the discovery of new uses for old ones, coupled with really large randomized controlled trials (RCTs), enabled effective treatments to be introduced, firstly in the acute phase, but probably more effectively for secondary prevention.

Keywords:   treatments, drug therapy, cardiovascular disease, coronary heart disease, coronary care, randomized controlled trials

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