The assessment and management of advanced cancer of the ovary
The assessment and management of advanced cancer of the ovary
Ovarian cancer is the seventh most-common cancer of women worldwide. Although it is generally regarded as a chemo-sensitive malignancy, the majority of women afflicted with this disease develop chemo-resistance and eventually die of their disease. Of the women diagnosed with ovarian cancer, only 15–20 per cent are curable with a combination of chemotherapy and surgery. However, when patients relapse, the prospect of cure diminishes, and the aims of treatment change to palliation of symptoms and prolongation of life. This chapter highlights some of the evidence-based treatment for decisions facing oncologists in the management of women with advanced or recurring ovarian cancer. It places emphasis on the role of chemotherapy in this setting. The aims of treatment in these patients differ considerably based on the progression of the disease, performance status of the patient, co-morbid illnesses, and the patient's individual wishes. Included in the chapter are three cases that highlight some of the clinical scenarios and different management decisions.
Keywords: ovarian cancer, treatment, management, women, advanced ovarian cancer, recurring ovarian cancer, role of chemotherapy, cases, clinical scenarios, management decisions
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