Epidemiological Methods in Life Course Research
Andrew Pickles, Barbara Maughan, and Michael Wadsworth
Abstract
Life course epidemiology is developing rapidly in the context of new knowledge about the biology of development and ageing and gene-environment interplay. This book is concerned with design, measurement, and analysis of life course data. Study design chapters are concerned with models of the life course development of risk, the effect of individual differences, the study of genetic effects, and intervention in life course designs. Analysis chapters deal with time-varying exposure, missingness, analysis of multivariate outcomes, estimation of causality, structural equation modelling, and trajec ... More
Life course epidemiology is developing rapidly in the context of new knowledge about the biology of development and ageing and gene-environment interplay. This book is concerned with design, measurement, and analysis of life course data. Study design chapters are concerned with models of the life course development of risk, the effect of individual differences, the study of genetic effects, and intervention in life course designs. Analysis chapters deal with time-varying exposure, missingness, analysis of multivariate outcomes, estimation of causality, structural equation modelling, and trajectory analysis. The intention is to provide a guide to the evaluation of interacting developmental, environmental, and genetic effects in studies of the processes and origins of risk, resilience, and ageing.
Keywords:
life course,
time-varying exposure,
missingness,
multivariate outcomes,
causality,
equation modelling,
trajectory analysis,
ageing,
epidemiological design
Bibliographic Information
| Print publication date: 2007 |
Print ISBN-13: 9780198528487 |
| Published to Oxford Scholarship Online: September 2009 |
DOI:10.1093/acprof:oso/9780198528487.001.0001 |
Authors
Affiliations are at time of print publication.
Andrew Pickles, editor
Professor of Epidemiological and Social Statistics, University of Manchester, UK
Barbara Maughan, editor
MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, Institute of Psychiatry, London, UK
Michael Wadsworth, editor
Retired Director of the MRC National Survey of Health and Development, University College London, London, UK
More
Less
