Jump to ContentJump to Main Navigation
The SynapseFunction, Plasticity, and Neurotrophism$
Users without a subscription are not able to see the full content.

Motoy Kuno

Print publication date: 1994

Print ISBN-13: 9780198546870

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198546870.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 20 January 2021

Functional plasticity at synapses

Functional plasticity at synapses

(p.89) 7 Functional plasticity at synapses
The Synapse

Motoy Kuno

Oxford University Press

Functional synaptic plasticity is a relatively longlasting alteration in the efficiency of synaptic transmission. In biophysical terms, the efficiency of synaptic transmission is determined by two parameters: how much transmitter is released from presynaptic terminals, and what size of postsynaptic response is produced per unit amount of transmitter. Consequently, plastic changes at synapses must be associated with changes in either one or both parameters. The principal questions concern how these changes are induced (acquisition or learning) and maintained (retention or memory). Depending on how long these changes persist, plasticity can be divided into short-term (minutes to hours) and long-term (days to years) alterations. This chapter first focuses on relatively straightforward forms of plastic changes and sees what substrates are involved. For this purpose, the chapter begins with short-term plasticity at the level of peripheral synapses.

Keywords:   synaptic plasticity, synaptic transmission, presynaptic terminals, postsynaptic response, peripheral synapses, short-term alteration

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .