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Greg Stuart, Nelson Spruston, and Michael Häusser

Print publication date: 2007

Print ISBN-13: 9780198566564

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198566564.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 28 January 2021

Dendrite development

Dendrite development

(p.68) (p.69) Chapter 3 Dendrite development

Jennifer Bestman

Jorge Santos Da Silva

Hollis T. Cline

Oxford University Press

The emergence of dendritic arbor structure in vivo occurs in the context of a developing functional nervous system. It is therefore of utmost importance to consider the interaction between intracellular signaling pathways and inputs from the environment, in the form of growth factors, synaptic inputs, and interactions with other cells. This chapter is written with a special emphasis on the activity-dependent regulation of dendritic arbor structure in the context of the development of functional neuronal circuits. After a brief description of dendritic arbor development and adult dendritic plasticity, it presents representative molecular and cellular mechanisms governing dendrite arbor architecture.

Keywords:   dendritic arbor, nervous system, signaling pathways, growth factors, synaptic inputs, dendritic plasticity

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