- Title Pages
- Chapter 1 Dendrite structure
- Chapter 2 Evolution and scaling of dendrites
- Chapter 3 Dendrite development
- Chapter 4 Molecular determinants of dendrite and spine development
- Chapter 5 RNA targeting, trafficking, and translation in dendrites
- Chapter 6 Organization and regulation of the postsynaptic density
- Chapter 7 Subcellular distribution of neurotransmitter receptors and voltage-gated ion channels
- Chapter 8 Neurotransmitter-gated ion channels in dendrites
- Chapter 9 Dendritic voltage-gated ion channels
- Chapter 10 Biochemical compartmentalization in dendrites
- Chapter 11 Spine calcium signaling
- Chapter 12 An historical perspective on modeling dendrites
- Chapter 13 A theoretical view of the neuron as a plastic input-output device
- Chapter 14 Dendritic integration
- Chapter 15 Dendrites as transmitters
- Chapter 16 Why have dendrites?
- Chapter 17 Short stories about small brains
- Chapter 18 Functional plasticity at dendritic synapses
- Chapter 19 Structural plasticity of dendrites
- Chapter 20 Dendrites and disease
- Chapter 21 Conclusion
Why have dendrites?
Why have dendrites?
A computational perspective
- (p.420) (p.421) Chapter 16 Why have dendrites?
Bartlett W. Mel
- Oxford University Press
This chapter is concerned with how dendritic trees may contribute to the information-processing functions of individual nerve cells in the CNS. After reviewing the history of ideas about dendritic integration, beginning with several influential modeling studies of the 1980s, it focuses on the pyramidal neuron of the cerebral cortex and hippocampus. It describes a sequence of models of increasing complexity, beginning with the classical “point neuron” model, and ending with a highly articulated single-neuron abstraction consisting of multiple integrative subunits organized into multiple processing layers.
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