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Aging of the GenomeThe dual role of DNA in life and death$
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Jan Vijg

Print publication date: 2007

Print ISBN-13: 9780198569237

Published to Oxford Scholarship Online: April 2010

DOI: 10.1093/acprof:oso/9780198569237.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 08 December 2021

Introduction: the coming of age of the genome

Introduction: the coming of age of the genome

(p.1) 1 Introduction: the coming of age of the genome
Aging of the Genome

Jan Vijg

Oxford University Press

This chapter sketches the major developments in the science of biology, from the Renaissance to the genome revolution, in two parallel lines: one that explains how we gradually gained a mechanistic understanding of how life perpetuates itself through random alterations in DNA, with aging of its carriers as the inevitable by-product; and a much more complicated learning curve that thus far has merely provided the starting points of how we hope to gain a more complete understanding of how life forms are ordered at the molecular level and how this order turns into disorder during aging.

Keywords:   aging, biology, genetics, genomics

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