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Aging of the GenomeThe dual role of DNA in life and death$
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Jan Vijg

Print publication date: 2007

Print ISBN-13: 9780198569237

Published to Oxford Scholarship Online: April 2010

DOI: 10.1093/acprof:oso/9780198569237.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 26 February 2021

Genome maintenance

Genome maintenance

Chapter:
(p.91) 4 Genome maintenance
Source:
Aging of the Genome
Author(s):

Jan Vijg

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198569237.003.0004

This chapter reviews the various genome-maintenance pathways that satisfy the specific need of DNA for stability, with a focus on eukaryotes and mammalian cells. Topics discussed include genome maintenance, DNA-damage signalling and cellular responses, DNA-repair mechanisms, and genome maintenance and aging.

Keywords:   DNA damage, aging, genome maintenance, cellular response, DNA repair, cellular signalling

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