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Addiction and ChoiceRethinking the relationship$
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Nick Heather and Gabriel Segal

Print publication date: 2016

Print ISBN-13: 9780198727224

Published to Oxford Scholarship Online: November 2016

DOI: 10.1093/acprof:oso/9780198727224.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 22 October 2020

The role of the insula in goal-directed drug seeking and choice in addiction

The role of the insula in goal-directed drug seeking and choice in addiction

Chapter:
(p.205) Chapter 12 The role of the insula in goal-directed drug seeking and choice in addiction
Source:
Addiction and Choice
Author(s):

Nasir H. Naqvi

Antoine Bechara

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198727224.003.0012

This chapter describes our current understanding of the role of the insula in addiction. It begins by summarizing the initial work by the authors showing the effects of insula lesions on smoking behavior. The chapter then summarizes more recent work demonstrating a role for the insula in affective, motivational, interoceptive, and decision-making functions that are relevant for addiction. A theoretical model is presented in which the insula plays a role in motivating addictive choices when there are high levels of conflict or risk. The clinical implications of this model are discussed.

Keywords:   insula, addiction, insula lesions, decision-making, theoretical model, addictive choices

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