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Dendrites$
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Dendrites

Greg Stuart, Nelson Spruston, and Michael Häusser

Print publication date: 2016

Print ISBN-13: 9780198745273

Published to Oxford Scholarship Online: May 2016

DOI: 10.1093/acprof:oso/9780198745273.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 22 January 2021

Functional plasticity at dendritic synapses

Functional plasticity at dendritic synapses

Chapter:
(p.505) Chapter 18 Functional plasticity at dendritic synapses
Source:
Dendrites
Author(s):

Jérôme Maheux

Robert C. Froemke

P. Jesper Sjöström

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198745273.003.0018

This chapter summarizes experiments and theory that are relevant to the role of dendrites in plasticity. Since the vast majority of synapses form connections onto the dendritic arbor of a neuron, synaptic plasticity is fundamentally a dendritic phenomenon. Dendrites integrate incoming information to elicit local dendritic spikes that help trigger plasticity mechanisms. However, synapses far from the soma may be relatively more isolated from axonally initiated action potentials, which are important—although not always required—for long-term synaptic plasticity. As the excitability of dendritic arbors is itself plastic, synaptic plasticity must be coordinated with dendritic plasticity for the control of neuronal computations and neural circuit functions.

Keywords:   dendrite, action potentials, synaptic plasticity, dendritic arbors, neural circuit, neuronal computation

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