Venous Thromboembolism in Advanced Disease: A clinical guide
Simon I R Noble, Miriam J Johnson, and Agnes Y Y Lee
Abstract
There is increasing recognition of the burden of venous thromboembolism (VTE) in patients with advanced incurable disease and the clinical, ethical, and philosophical challenges they may pose. With a growing elderly population and oncological therapies helping patients live longer with malignant disease, VTE is likely to be an ongoing problem. Whilst presentation, diagnosis, and treatment of VTE in general medicine are well established, its management within the palliative care setting is less clear-cut. Clinical presentation is often masked by other palliative symptoms, and symptoms can be co ... More
There is increasing recognition of the burden of venous thromboembolism (VTE) in patients with advanced incurable disease and the clinical, ethical, and philosophical challenges they may pose. With a growing elderly population and oncological therapies helping patients live longer with malignant disease, VTE is likely to be an ongoing problem. Whilst presentation, diagnosis, and treatment of VTE in general medicine are well established, its management within the palliative care setting is less clear-cut. Clinical presentation is often masked by other palliative symptoms, and symptoms can be consistent with those of other conditions; diagnosis is therefore underappreciated, and the condition can be difficult to manage. Bringing together international contributions from the field of VTE and palliative care, this book explores the increasing challenges faced by healthcare professionals when managing VTE in advanced disease. Topics such as the epidemiology and pathogenesis of the condition are discussed. It appraises the current evidence informing the prevention, diagnosis, and treatment of VTE, with particular emphasis on its application to patients with incurable malignancy and non-malignant disease. Chapters are illustrated with key learning points and, where appropriate, case studies are presented to illustrate the decision-making processes that may occur when balancing the evidence with its impact on patient quality of life.
Keywords:
venous thromboembolism,
oncological therapies,
malignant disease,
palliative care,
epidemiology,
pathogenesis
Bibliographic Information
| Print publication date: 2008 |
Print ISBN-13: 9780199232048 |
| Published to Oxford Scholarship Online: November 2011 |
DOI:10.1093/acprof:oso/9780199232048.001.0001 |
Authors
Affiliations are at time of print publication.
Simon I R Noble, editor
Clinical Senior Lecturer and Honorary Consultant in Palliative Medicine, Cardiff University and the Royal Gwent Hospital, Wales, UK
Miriam J Johnson, editor
Senior Lecturer in Palliative Medicine, Hull-York Medical School, and Honorary Consultant to St. Catherine's Hospice, North Yorkshire, UK
Author Webpage
Agnes Y Y Lee, editor
Associate Professor, Division of Hematology and Thromboembolism, Department of Medicine, McMaster University; Acting Head, Thromboembolism Service, Hamilton Health Sciences Henderson Hospital, Hamilton, Ontario, Canada
Author Webpage
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