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Ancestral Sequence Reconstruction$
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David A Liberles

Print publication date: 2007

Print ISBN-13: 9780199299188

Published to Oxford Scholarship Online: September 2008

DOI: 10.1093/acprof:oso/9780199299188.001.0001

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Reconstructing the ancestral eukaryote: lessons from the past

Reconstructing the ancestral eukaryote: lessons from the past

(p.103) CHAPTER 10 Reconstructing the ancestral eukaryote: lessons from the past
Ancestral Sequence Reconstruction

Mary J. O'Connell

James O. McInerney

Oxford University Press

Reconstructing ancestral proteins relies heavily on accurate phylogeny reconstruction. This is a challenging area particularly for early eukaryote evolution. Despite decades of extensive studies to resolve the structure of the deepest branches of the Eukaryota, a generally accepted phylogenetic reconstruction has not been achieved. This chapter explores the relationships of the three crown eukaryota and the root of the animal kingdom itself. It describes the methodological developments that have aided the field of early eukaryote evolution and the biases that exist in certain methods and data.

Keywords:   eukaryote evolution, phylogenetic reconstruction, three crown eukaryota, ancestral proteins

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