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Placebo EffectsUnderstanding the mechanisms in health and disease$
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Fabrizio Benedetti

Print publication date: 2008

Print ISBN-13: 9780199559121

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780199559121.001.0001

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Gastrointestinal and genitourinary disorders

Gastrointestinal and genitourinary disorders

(p.195) Chapter 8 Gastrointestinal and genitourinary disorders
Placebo Effects

Fabrizio Benedetti

Oxford University Press

Irritable bowel syndrome is one of the best models of gastrointestinal disorders to use as a model for understanding placebo mechanisms. Several brain regions are inhibited by a placebo treatment in patients suffering from irritable bowel syndrome. In general, gastrointestinal symptoms can be conditioned, which indicates that learning may play an important role. Subjective symptoms are more affected than objective symptoms in genitourinary disorders. In addition, expectation is known to be crucially involved in sexual functions.

Keywords:   irritable bowel syndrome, pain, brain imaging, expectation, conditioning, learning, urologic diseases, sexual functions

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