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Evidence-based Public HealthEffectiveness and efficiency$
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Amanda Killoran and Mike P. Kelly

Print publication date: 2009

Print ISBN-13: 9780199563623

Published to Oxford Scholarship Online: February 2010

DOI: 10.1093/acprof:oso/9780199563623.001.0001

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Developing evidence-based guidance for health technologies: the NICE experience

Developing evidence-based guidance for health technologies: the NICE experience

(p.398) Chapter 27 Developing evidence-based guidance for health technologies: the NICE experience
Evidence-based Public Health

David Barnett,

Andrew Stevens,

Meindert Boysen,

Carole Longson

Oxford University Press

The National Institute for Health and Clinical Excellence (NICE) approach to appraisal of health care technologies was established in 1999 on the basis of three guiding principles: to provide guidance and standards to the National Health Service (NHS) based on clinical and cost-effectiveness of methods of treating ill health; to resolve uncertainty amongst both health care professionals and patients regarding the best approach to therapy; and consequently, to minimize inappropriate variation in clinical practice. The recipients of NICE guidance are primarily clinical professionals, commissioners of health care as well as the patients and carers that use the NHS. However, the ‘audience’ for NICE guidance also includes the manufacturers, the media, politicians, the general public, and the international community. This chapter provides an overview of the processes and methods used to appraise health care technologies, typically a new drug. It illustrates the appraisal of cost-effectiveness of health technologies using the ‘reference case’. It then highlights the role of ethical, legal, media, and political influences on the development of health technologies guidance.

Keywords:   Clinical Excellence, health care technologies, new drug evaluation, technologies guidance

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