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TobaccoScience, policy and public health$
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Peter Boyle, Nigel Gray, Jack Henningfield, John Seffrin, and Witold Zatonski

Print publication date: 2010

Print ISBN-13: 9780199566655

Published to Oxford Scholarship Online: September 2010

DOI: 10.1093/acprof:oso/9780199566655.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 23 January 2021

Tobacco carcinogenesis: mechanisms and biomarkers

Tobacco carcinogenesis: mechanisms and biomarkers

(p.127) Chapter 7 Tobacco carcinogenesis: mechanisms and biomarkers

Stephen S. Hecht

Oxford University Press

The indisputable relationship between the world's most widespread exogenous chemical carcinogen exposure — tobacco smoke — and cancer, provides a framework for a better understanding of cancer mechanisms in general, particularly the interaction between carcinogen exposure and host factors, and for the development of novel preventive and therapeutic strategies. Furthermore, the biomarkers that are developed in this research can be applied in the approaching era of tobacco product regulation. This chapter discusses the mechanisms of tumour induction by tobacco carcinogens and the status of tobacco carcinogen biomarkers.

Keywords:   tobacco smoke, cigarette smoke, cancer, tumour induction, tobacco carcinogens, biomarkers

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