- Title Pages
- Preface
- Contributors
- Abbreviations
- Chapter 1 Introduction
- Part 1 History
- Chapter 2 Memory before and after H.M.: an impressionistic historical perspective
- Chapter 3 Memory disorders and epilepsy during the nineteenth century
- Part 2 Overviews of memory and epilepsy
- Chapter 4 Interictal memory disturbance: a comparative phenomenology and epidemiology of memory impairment in epilepsies
- Chapter 5 Long-term follow-up of memory in patients with epilepsy
- Chapter 6 Memory in children with epilepsy
- Part 3 Ictal and interictal memory phenomena
- Chapter 7 <i>Déjà</i> experiences in epilepsy: contributions from memory research
- Chapter 8 The syndrome of transient epileptic amnesia
- Chapter 9 Effects of epileptiform EEG discharges on cognitive function
- Part 4 Assessment
- Chapter 10 Neuropsychological assessment of memory in patients with epilepsy
- Chapter 11 Memory assessment in intracarotid anaesthetic procedures: history and current status
- Chapter 12 Epilepsy and the study of spatial memory using virtual reality
- Part 5 Remote memory and psychiatric disorders
- Chapter 13 Remote memory and temporal lobe epilepsy
- Chapter 14 Electroconvulsive therapy for depression and autobiographical memory
- Chapter 15 Psychiatric aspects of memory disorders in epilepsy
- Part 6 Imaging and event-related potentials (ERPs)
- Chapter 16 Structural imaging and neuropathological correlates of memory in epilepsy
- Chapter 17 Functional imaging of memory in epilepsy
- Chapter 18 Electrophysiological studies of memory in epilepsy
- Part 7 Intracranial stimulation and recording
- Chapter 19 Memory and epilepsy in nonhuman animals
- Chapter 20 Hippocampal electrical stimulation and localisation of long-term episodic memory
- Chapter 21 Interrelationships between epilepsy, sleep, and memory
- Chapter 22 Mapping memories in the medial temporal lobe: contributions from single-neuron recordings in patients with epilepsy
- Part 8 Management and outcome
- Chapter 23 Anticonvulsants and memory
- Chapter 24 Effects of amygdalohippocampectomy versus corticoamygdalohippocampectomy on memory and nonmemory cognitive functions
- Chapter 25 Memory rehabilitation for people with epilepsy
- Author index
- Subject index
Anticonvulsants and memory
Anticonvulsants and memory
- Chapter:
- (p.397) Chapter 23 Anticonvulsants and memory
- Source:
- Epilepsy and Memory
- Author(s):
Joanne Taylor
Gus A. Baker
- Publisher:
- Oxford University Press
People with epilepsy not only report subjective cognitive complaints, but they also demonstrate poorer performance on objective neuropsychological tests when compared to those without the condition. A number of studies have shown reduced memory and learning, attention, and concentration problems, slower information processing, language deficits, and executive dysfunction. This chapter reviews the evidence in respect of the specific effects of antiepileptic drugs (AEDs) on memory functioning. Despite between twenty-five and thirty years documenting the effects of antiepileptic drug medication, no definitive conclusions have been drawn in respect to the impact of individual AEDs on memory functioning. However, there is growing evidence that suggests that many of the newer antiepileptic drugs — used as monotherapy and given at therapeutic ranges — are unlikely to produce significant cognitive problems, although there are some exceptions, for example, topiramate and zonisamide.
Keywords: epilepsy, antiepileptic drugs, memory function, topiramate, zonisamide
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- Title Pages
- Preface
- Contributors
- Abbreviations
- Chapter 1 Introduction
- Part 1 History
- Chapter 2 Memory before and after H.M.: an impressionistic historical perspective
- Chapter 3 Memory disorders and epilepsy during the nineteenth century
- Part 2 Overviews of memory and epilepsy
- Chapter 4 Interictal memory disturbance: a comparative phenomenology and epidemiology of memory impairment in epilepsies
- Chapter 5 Long-term follow-up of memory in patients with epilepsy
- Chapter 6 Memory in children with epilepsy
- Part 3 Ictal and interictal memory phenomena
- Chapter 7 <i>Déjà</i> experiences in epilepsy: contributions from memory research
- Chapter 8 The syndrome of transient epileptic amnesia
- Chapter 9 Effects of epileptiform EEG discharges on cognitive function
- Part 4 Assessment
- Chapter 10 Neuropsychological assessment of memory in patients with epilepsy
- Chapter 11 Memory assessment in intracarotid anaesthetic procedures: history and current status
- Chapter 12 Epilepsy and the study of spatial memory using virtual reality
- Part 5 Remote memory and psychiatric disorders
- Chapter 13 Remote memory and temporal lobe epilepsy
- Chapter 14 Electroconvulsive therapy for depression and autobiographical memory
- Chapter 15 Psychiatric aspects of memory disorders in epilepsy
- Part 6 Imaging and event-related potentials (ERPs)
- Chapter 16 Structural imaging and neuropathological correlates of memory in epilepsy
- Chapter 17 Functional imaging of memory in epilepsy
- Chapter 18 Electrophysiological studies of memory in epilepsy
- Part 7 Intracranial stimulation and recording
- Chapter 19 Memory and epilepsy in nonhuman animals
- Chapter 20 Hippocampal electrical stimulation and localisation of long-term episodic memory
- Chapter 21 Interrelationships between epilepsy, sleep, and memory
- Chapter 22 Mapping memories in the medial temporal lobe: contributions from single-neuron recordings in patients with epilepsy
- Part 8 Management and outcome
- Chapter 23 Anticonvulsants and memory
- Chapter 24 Effects of amygdalohippocampectomy versus corticoamygdalohippocampectomy on memory and nonmemory cognitive functions
- Chapter 25 Memory rehabilitation for people with epilepsy
- Author index
- Subject index